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Xin-Jian LI MD, Min-Na CHENG MPH, Yu-Heng WANG MD, Sun MIAO MPH, Zong-Qi ZHANG PhD, Yi-Sheng CHEN MD, Wei LU PhD,
《医学前沿(英文)》 2010年 第4卷 第1期 页码 67-70 doi: 10.1007/s11684-010-0023-8
关键词: hypertension community pharmacological adherence control of blood pressure
Hudan Pan, Yanfang Zheng, Zhongqiu Liu, Zhongwen Yuan, Rutong Ren, Hua Zhou, Ying Xie, Liang Liu
《医学前沿(英文)》 2019年 第13卷 第5期 页码 564-574 doi: 10.1007/s11684-018-0676-2
关键词: rheumatoid arthritis traditional Chinese medicine pharmacological mechanism metabolism adjuvant-induced arthritis omics analysis
Poor adherence to P2Y12 antagonists increased cardiovascular risks in Chinese PCI-treated patients
null
《医学前沿(英文)》 2017年 第11卷 第1期 页码 53-61 doi: 10.1007/s11684-017-0502-2
Low adherence to secondary prevention medications (ATM) of patients after acute coronary syndrome (ACS) is associated with poor clinical outcomes. However, literature provides limited data on assessment of ATM and risks associated with poor in Chinese patients with ACS. In the current work, ATM was assessed in consecutively recruited patients with ACS in Tongji Hospital from November 5, 2013 to December 31, 2014. A total of 2126 patients were classified under low adherence (proportion of days covered (PDC)<50%) and high adherence (PDC>50%) groups based on their performance after discharge. All patients were followed up at the 1st, 6th, and 12th month of discharge while recording ATM and major adverse cardiac events (MACE). Bivariate logistic regression was used to identify the factors associated with ATM. Cox regression was used to analyze the association between ATM and MACE within one year after discharge. Results showed that coronary artery bypass grafting (CABG) alone had significantly lower proportion of high adherence to P2Y12 antagonists (83.0% vs. 90.7%, P<0.01) than patients treated with percutaneous coronary intervention (PCI) only. Moreover, in patients undergoing PCI, high adherence to P2Y12 antagonists decreased the risk of MACE (hazard ratio=0.172, 95% confidence interval: 0.039–0.763; P=0.021). In conclusion, PCI-treated patients are more prone to remaining adherent to medications than CABG-treated patients. High adherence to P2Y12 antagonists was associated with lower risk of MACE.
关键词: acute coronary syndromes adherence to secondary prevention medications clinical outcome
Biological properties and clinical applications of berberine
Danyang Song, Jianyu Hao, Daiming Fan
《医学前沿(英文)》 2020年 第14卷 第5期 页码 564-582 doi: 10.1007/s11684-019-0724-6
关键词: berberine Coptis chinensis pharmacological properties mechanism clinical applications
A novel intravenous general anesthetic--- emulsified isoflurane: from bench to bedside
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《医学前沿(英文)》 2012年 第6卷 第4期 页码 381-387 doi: 10.1007/s11684-012-0229-z
Application of volatile anesthetics greatly alters modern medicine. There are obvious advantages of volatile anesthetics such as strong anesthetic potency, rapid onset and elimination through respiration system. Isoflurane is one of the most widely used volatile anesthetics in clinic. Emulsified isoflurane, the emulsion of isoflurane, is a novel intravenous general anesthetic. With the development of emulsified isoflurane in the past fifteen years, its utility has spread from intravenous general anesthesia to various fields including regional anesthesia, organ protection, as well as anesthetic pharmacological study. In this review, we will summarize literatures of emulsified isoflurane about its history, clinical application and future potential utility in the above mentioned fields.
关键词: emulsified isoflurane (EI) general anesthesia regional anesthesia organ protection anesthetic pharmacological study
design of novel proton-pump inhibitors with reduced adverse effects
Xiaoyi Li, Hong Kang, Wensheng Liu, Sarita Singhal, Na Jiao, Yong Wang, Lixin Zhu, Ruixin Zhu
《医学前沿(英文)》 2019年 第13卷 第2期 页码 277-284 doi: 10.1007/s11684-018-0630-3
关键词: proton-pump inhibitor adverse effect pharmacological mechanism toxicological mechanism pKa calculation
标题 作者 时间 类型 操作
Effectiveness of lifestyle intervention for hypertension in Shanghai communities: Results from the Shanghai Hypertension Detail Management Program
Xin-Jian LI MD, Min-Na CHENG MPH, Yu-Heng WANG MD, Sun MIAO MPH, Zong-Qi ZHANG PhD, Yi-Sheng CHEN MD, Wei LU PhD,
期刊论文
Deciphering the pharmacological mechanism of Guan-Jie-Kang in treating rat adjuvant-induced arthritis
Hudan Pan, Yanfang Zheng, Zhongqiu Liu, Zhongwen Yuan, Rutong Ren, Hua Zhou, Ying Xie, Liang Liu
期刊论文
Poor adherence to P2Y12 antagonists increased cardiovascular risks in Chinese PCI-treated patients
null
期刊论文
Biological properties and clinical applications of berberine
Danyang Song, Jianyu Hao, Daiming Fan
期刊论文